Core binding factor

The Core binding factor (CBF) is a group of heterodimeric transcription factors.

Core binding factors are composed of:

  • a non-DNA-binding CBFβ chain (CBFB)
  • a DNA-binding CBFα chain (RUNX1, RUNX2, RUNX3)

References
  • de Bruijn M, Speck N (2004). "Core-binding factors in hematopoiesis and immune function". Oncogene. 23 (24): 4238–48. doi:10.1038/sj.onc.1207763. PMID 15156179.
  • Core+Binding+Factors at the US National Library of Medicine Medical Subject Headings (MeSH)
  • AI-10-49


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