Endralazine

Endralazine is an antihypertensive of the hydrazinophthalazine chemical class.[1] It is not approved for use in the United States.

Endralazine
Clinical data
ATC code
Identifiers
IUPAC name
  • 6-benzoyl-3-hydrazinyl-5H,6H,7H,8H-pyrido[4,3-c]pyridazine
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC14H15N5O
Molar mass269.308 g·mol−1
3D model (JSmol)
SMILES
  • c1ccc(cc1)C(=O)N2CCc3c(c/c(=N/N)/[nH]n3)C2
InChI
  • InChI=1S/C14H15N5O/c15-16-13-8-11-9-19(7-6-12(11)17-18-13)14(20)10-4-2-1-3-5-10/h1-5,8H,6-7,9,15H2,(H,16,18) N
  • Key:ALAXZYHFVBSJKZ-UHFFFAOYSA-N N
 NY (what is this?)  (verify)

References
  1. Meredith PA, Elliott HL, McSharry DR, Kelman AW, Reid JL (July 1983). "The pharmacokinetics of endralazine in essential hypertensives and in normotensive subjects". British Journal of Clinical Pharmacology. 16 (1): 27–32. doi:10.1111/j.1365-2125.1983.tb02139.x. PMC 1427948. PMID 6882620.
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