Ibacitabine

Ibacitabine (or ibacitabin,[1] or 5-iodo-2'-deoxycytidine ) is an antiviral drug. It is topically applied to treat herpes labialis.[2]

Ibacitabine
Names
Preferred IUPAC name
4-Amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidin-2(1H)-one
Identifiers
CAS Number
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.009.337
KEGG
PubChem CID
UNII
InChI
  • InChI=1S/C9H12IN3O4/c10-4-2-13(9(16)12-8(4)11)7-1-5(15)6(3-14)17-7/h2,5-7,14-15H,1,3H2,(H2,11,12,16)/t5-,6+,7+/m0/s1 N
    Key: WEVJJMPVVFNAHZ-RRKCRQDMSA-N N
  • InChI=1/C9H12IN3O4/c10-4-2-13(9(16)12-8(4)11)7-1-5(15)6(3-14)17-7/h2,5-7,14-15H,1,3H2,(H2,11,12,16)/t5-,6+,7+/m0/s1
    Key: WEVJJMPVVFNAHZ-RRKCRQDMBC
SMILES
  • OCC1[C@@H](O)C[C@@H](O1)N2C=C(I)C(N)=NC2=O
Properties
Chemical formula
 C9H12IN3O4
Molar mass 353.11375
Pharmacology
D06BB08 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

References
  1. Serpentier-Daude, A.; Collet, E.; Didier, A. F.; Touraud, J. P.; Sgro, C.; Lambert, D. (February 2000). "[Contact dermatitis to topical antiviral drugs]". Ann Dermatol Venereol. 127 (2): 191–3. PMID 10739980.
  2. Groot, Anton C. de (2021). Topical drugs (First ed.). Boca Raton, FL: CRC Press. p. 421. ISBN 9781000367867.




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