Lanthanum carbonate

Lanthanum carbonate, La2(CO3)3, is the salt formed by lanthanum(III) cations and carbonate anions. It is an ore of lanthanum metal (bastnäsite), along with monazite.

Lanthanum carbonate
Names
IUPAC name
Lanthanum carbonate
Identifiers
CAS Number
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.008.728
EC Number
  • 209-599-5
PubChem CID
UNII
InChI
  • InChI=1S/3CH2O3.2La/c3*2-1(3)4;;/h3*(H2,2,3,4);;/q;;;2*+3/p-6 Y
    Key: NZPIUJUFIFZSPW-UHFFFAOYSA-H Y
  • InChI=1/3CH2O3.2La/c3*2-1(3)4;;/h3*(H2,2,3,4);;/q;;;2*+3/p-6
    Key: NZPIUJUFIFZSPW-CYFPFDDLAT
SMILES
  • [La+3].[La+3].O=C([O-])[O-].[O-]C([O-])=O.[O-]C([O-])=O
Properties
Chemical formula
 La2(CO3)3
Molar mass 457.838 g/mol
Appearance White powder, hygroscopic
Density 2.6–2.7 g/cm3
Melting point decomposes
Solubility in water
 negligible
Solubility soluble in acids
Pharmacology
V03AE03 (WHO)
Related compounds
Other anions
 Lanthanum(III) oxide
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

Chemistry

Lanthanum carbonate is used as a starting material in lanthanum chemistry, particularly in forming mixed oxides, for example

  • for production of lanthanum strontium manganite, primarily for solid oxide fuel cell applications;
  • for production of certain high-temperature superconductors, such as La2-xSrxCuO2.

Medical uses

Lanthanum carbonate is used in medicine as a phosphate binder.[1] As a medication it is sold under the trade name Fosrenol by the pharmaceutical company Shire Pharmaceuticals. Due to its large size (1000 mg tablet is 2.2 cm in diameter), it may be possible to choke on the tablet if it is not chewed. It is prescribed for the treatment of hyperphosphatemia, primarily in patients with chronic kidney disease. It is taken with meals and binds to dietary phosphate, preventing phosphate from being absorbed by the intestine. For cats with hyperphosphatemia it is available under the trade name Renalzin by Bayer Animal Health.[2]

However, when lanthanum carbonate is used for treating hyperphosphatemia, its side effects, namely myalgia, muscular cramping, and peripheral edema, should be clinically monitored.[3]

Other applications

Lanthanum carbonate is also used for the tinting of glass, for water treatment, and as a catalyst for hydrocarbon cracking.

References
  1. Editorial Staff (December 2004). "Lanthanum Carbonate". All Micromedex Systems. Micromedex, Inc. Archived from the original on 2007-09-14. Retrieved 2007-11-25.
  2. Bayer Animal Health (26 September 2008). "Bayer Animal Health launches Renalzin for Cats" (PDF). Archived from the original (PDF) on 7 July 2011. Retrieved 2008-09-30.
  3. Tonelli, Marcello; Pannu, Neesh; Manns, Braden (2010). "Oral Phosphate Binders in Patients with Kidney Failure". New England Journal of Medicine. 362 (14): 1312–24. doi:10.1056/NEJMra0912522. PMID 20375408. S2CID 22322676.
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