Pemphigus vegetans

Pemphigus vegetans is a localized form of pemphigus vulgaris.[1] in which there is a localized vegetating papillomatous response. The eroded areas do not heal like usual but form papillomatous growth and vegetation.

Pemphigus vegetans
SpecialtyDermatology 
See also: List of target antigens in pemphigus

Accounts for 1-2% of pemphigus cases and is a relatively benign variant of pemphigus vulgaris. Two forms are recognized:

  • Pemphigus vegetans of Neumann is a localized disease of pemphigus vulgaris slightly more extensive than pemphigus vegetans of Hallopeau.[1] : 568  This type is more common and characterized by early lesions similar to Pemphigus Vulgaris with large bullae and erosive areas. Healing is through formation of granulation tissue. It is named for the Austrian Dermatologist, Isidor Neumann.
  • Pemphigus vegetans of Hallopeau is a disease of localized pemphigus vulgaris.[1] : 568  It is named for François Henri Hallopeau. This type is less aggressive and has pustules not bullae. These pustules heal by verrucous hyperkeratotic vegetations.

See also

References
  1. Irwin M. Freedberg; et al., eds. (2003). Fitzpatrick's dermatology in general medicine (6th ed.). New York, NY [u.a.]: McGraw-Hill. p. 558. ISBN 978-0-07-138076-8.


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