Reproductive biology

Human reproductive biology is primarily controlled through hormones, which send signals to the human reproductive structures to influence growth and maturation. These hormones are secreted by endocrine glands, and spread to different tissues in the human body. In humans, the pituitary gland synthesizes hormones used to control the activity of endocrine glands.[3]

Internal and external organs are included in the reproductive system. There are two reproductive systems including the male and female, which contain different organs from one another. These systems work together in order to produce offspring.[4]

The female reproductive system includes the structures involved in ovulation, fertilization, development of an embryo, and birth.[3]

Human female reproductive structures.

These structures include:

Human male reproductive structures.

• Ovaries
• Oviducts
• Uterus
• Vagina
• Mammary Glands

Estrogen is one of the sexual reproductive hormones that aid in the sexual reproductive system of the female.[2]

The male reproductive system includes testes, rete testis, efferent ductules, epididymis, sex accessory glands, sex accessory ducts and external genitalia.[3]

Testosterone, an androgen, although present in both males and females, is relatively more abundant in males. Testosterone serves as one of the major sexual reproductive hormones in the male reproductive system However, the enzyme aromatase is present in testes and capable of synthesizing estrogens from androgens.[2] Estrogens are present in high concentrations in luminal fluids of the male reproductive tract.[5] Androgen and estrogen receptors are abundant in epithelial cells of the male reproductive tract.[6]

Spermatogenesis is the production of sperm cells in the testis. In mature testes primordial germ cells divide mitotically to form the spermatogonia, which in turn generate spermatocytes by mitosis.[10] Then each spermatocyte gives rise to four spermatids through meiosis.[10] Spermatids are now haploid and undergo differentiation into sperm cells.[10] Later in reproduction the sperm will fuse with a female oocyte to form the zygote.

Oogenesis is the formation of a cell who will produce one ovum and three polar bodies.[10] Oogenesis begins in the female embryo with the production of oogonia from primordial germ cells. Like spermatogenesis, the primordial germ cell undergo mitotic division to form the cells that will later undergo meiosis, but will be halted at the prophase I stage.[10] This is known as the primary oocyte. Human females are born with all the primary oocytes they will ever have.[10] Starting at puberty the process of meiosis can complete resulting in the secondary oocyte and the first polar body.[10] The secondary oocyte can later be fertilized with the male sperm.