Sex cords

In embryogenesis, the sex cords (primitive sex cords, primitive seminiferous cords, or gonadal cords) are structures that develop from the genital ridges that further differentiate based on an embryo's sex. After sexual differentiation, at day 49, the sex cords in females become the cortical cords, also called secondary cords. After further development, they become the ovarian follicles. The sex cords in males become the testis cords by the action of the testis-determining factor protein, which helps to develop and nourish the Sertoli cells.

Sex cords
Details
Precursorgenital ridge
Gives rise totestis cords, cortical cords
SystemReproductive system
Identifiers
Latinchorda sexualis primordialis gonadalis
TEcords_by_E5.7.1.1.0.0.7 E5.7.1.1.0.0.7
Anatomical terminology

The testis cords are precursors to the rete testis. They play several different roles in the development of the male genitals.[1] The primitive sex cords originate from the proliferation of the epithelium of the two genital ridges. These epithelial cells (from the genital ridges) penetrate and invade the underlying mesenchyme to form the primitive sex cords.[2] This occurs shortly before and during the arrival of the primordial germ cells (PGCs) to the paired genital ridges.[3]

See also

References

  1. Yao HH, Capel B (2002). "Disruption of testis cords by cyclopamine or forskolin reveals independent cellular pathways in testis organogenesis". Dev. Biol. 246 (2): 356–65. doi:10.1006/dbio.2002.0663. PMC 4073602. PMID 12051821.
  2. Sadler, T.W. (2010). Langman's medical embryology (11th ed.). Philadelphia: Lippincott William & Wilkins. pp. 246–247. ISBN 9780781790697. OCLC 227928523.
  3. Sadler, T.W. (2015). Langman's medical embryology (13th ed.). Philadelphia: Wolters Kluwer. ISBN 9781469897806. OCLC 885475111.


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