Small intestine cancer

Small intestine cancer is a cancer of the small intestine. It is relatively rare compared to other gastrointestinal malignancies such as gastric cancer (stomach cancer) and colorectal cancer.[1][2]

Small intestine cancer
Other namesSmall bowel cancer, cancer of the small bowel
Picture of a carcinoid tumour that encroaches into lumen of the small bowel. Pathology specimen. The prominent folds are plicae circulares, a characteristic of small bowel.
SpecialtyGastroenterology, general surgery, oncology
Symptomsvomiting blood, blood in the stool

Small intestine cancer can be subdivided into duodenal cancer (the first part of the small intestine) and cancer of the jejunum and ileum (the latter two parts of the small intestine). Duodenal cancer has more in common with stomach cancer, while cancer of the jejunum and ileum have more in common with colorectal cancer. Five-year survival rates are 65%.[3]

Histopathologic types

Relative incidence of histopathologic types of small intestine cancers, and their prognoses.[4]

Subtypes of small intestine cancer include:

Risk factors

Endoscopic image of adenocarcinoma of duodenum seen in the post-bulbar duodenum.

Risk factors for small intestine cancer include:[5][6]

Benign tumours and conditions that may be mistaken for cancer of the small bowel:

Additional images

References

  1. "Gastric Cancer". The Lecturio Medical Concept Library. Retrieved 22 July 2021.
  2. "Colon Cancer Treatment (PDQ®)". NCI. May 12, 2014. Archived from the original on July 5, 2014. Retrieved June 29, 2014.
  3. "SEER Stat Fact Sheets: Small Intestine Cancer". NCI. Retrieved 18 June 2014.
  4. Qubaiah, O.; Devesa, S. S.; Platz, C. E.; Huycke, M. M.; Dores, G. M. (2010). "Small Intestinal Cancer: a Population-Based Study of Incidence and Survival Patterns in the United States, 1992 to 2006". Cancer Epidemiology, Biomarkers & Prevention. 19 (8): 1908–1918. doi:10.1158/1055-9965.EPI-10-0328. ISSN 1055-9965. PMC 2919612. PMID 20647399.
  5. Delaunoit T, Neczyporenko F, Limburg PJ, Erlichman C (March 2005). "Pathogenesis and risk factors of small bowel adenocarcinoma: a colorectal cancer sibling?". Am. J. Gastroenterol. 100 (3): 703–10. PMID 15743371.
  6. Chen AC, Neugut AI. Malignant Neoplasms of the Small Intestine. eMedicine.com. URL: http://www.emedicine.com/MED/topic2651.htm. Accessed on: June 2, 2006.
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