Tiazesim

Tiazesim (INN), or thiazesim (BAN, USAN), previously sold under the brand name Altinil, is a heterocyclic antidepressant related to the tricyclic antidepressants (TCAs) which, first introduced in 1966 by Squibb Corporation (now Bristol-Myers Squibb), has since been discontinued and is no longer marketed.[1][2]

Tiazesim
Clinical data
Trade namesAltinil
Other namesThiazesim; Thiazenone; SQ-10496
Routes of
administration		By mouth
ATC code
  • None
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
IUPAC name
  • 5-[2-(dimethylamino)ethyl]-2-phenyl-2,3-dihydro-1,5-benzothiazepin-4(5H)-one
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
Chemical and physical data
FormulaC19H22N2OS
Molar mass326.46 g·mol−1
3D model (JSmol)
SMILES
  • CN(C)CCN1C(=O)CC(SC2=CC=CC=C21)C3=CC=CC=C3
InChI
  • InChI=1S/C19H22N2OS/c1-20(2)12-13-21-16-10-6-7-11-17(16)23-18(14-19(21)22)15-8-4-3-5-9-15/h3-11,18H,12-14H2,1-2H3
  • Key:QJJXOEFWXSQISU-UHFFFAOYSA-N

See also

References
  1. Ganellin CR, Triggle DJ, Macdonald F (1997). Dictionary of pharmacological agents. CRC Press. p. 1973. ISBN 978-0-412-46630-4. Retrieved 29 November 2011.
  2. The United States patents quarterly. 1969. Retrieved 1 May 2012.



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