Estriatina

Estriatina
Estructuras disponibles
PDB	Buscar ortólogos: PDBe, RCSB
Identificadores
Símbolos	STRN (HGNC: 11424) MGC125642; SG2NA
Identificadores; externos	EBI: STRN; GeneCards: Gen STRN; UniProt: STRN;
Locus	Cr. 2 p22.2
	Referencias: AmiGO / QuickGO
Ortólogos
Humano	Ratón
6801
O43815	n/a
NP_003153	n/a

La estriatina (STRN) es una proteína de unión a calmodulina codificada en humanos por el gen STRN.[1][2][3]

Interacciones

La estriatina ha demostrado ser capaz de interaccionar con:

STK25[4]
PDCD10[4]
CTTNBP2[4]
TRAF3IP3[4]
STRN3[4]
MOBKL3[4]
STK24[5][4]
PPP2CA[4]
RP6-213H19.1[4]
PPP2R1A[4]
CTTNBP2NL[4]
FAM40A[4]
Receptor de estrógeno alfa[6]

Referencias

Moqrich A, Mattei MG, Bartoli M, Rakitina T, Baillat G, Monneron A, Castets F (Sep de 1998). «Cloning of human striatin cDNA (STRN), gene mapping to 2p22-p21, and preferential expression in brain». Genomics 51 (1): 136-9. PMID 9693043. doi:10.1006/geno.1998.5342.
Castets F, Bartoli M, Barnier JV, Baillat G, Salin P, Moqrich A, Bourgeois JP, Denizot F, Rougon G, Calothy G, Monneron A (Oct de 1996). «A novel calmodulin-binding protein, belonging to the WD-repeat family, is localized in dendrites of a subset of CNS neurons». J Cell Biol 134 (4): 1051-62. PMC 2120968. PMID 8769426.
«Entrez Gene: STRN striatin, calmodulin binding protein».
Goudreault, Marilyn; D'Ambrosio Lisa M, Kean Michelle J, Mullin Michael J, Larsen Brett G, Sanchez Amy, Chaudhry Sidharth, Chen Ginny I, Sicheri Frank, Nesvizhskii Alexey I, Aebersold Ruedi, Raught Brian, Gingras Anne-Claude (Jan. de 2009). «A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein». Mol. Cell Proteomics (United States) 8 (1): 157-71. PMID 18782753. doi:10.1074/mcp.M800266-MCP200.
Ewing, Rob M; Chu Peter, Elisma Fred, Li Hongyan, Taylor Paul, Climie Shane, McBroom-Cerajewski Linda, Robinson Mark D, O'Connor Liam, Li Michael, Taylor Rod, Dharsee Moyez, Ho Yuen, Heilbut Adrian, Moore Lynda, Zhang Shudong, Ornatsky Olga, Bukhman Yury V, Ethier Martin, Sheng Yinglun, Vasilescu Julian, Abu-Farha Mohamed, Lambert Jean-Philippe, Duewel Henry S, Stewart Ian I, Kuehl Bonnie, Hogue Kelly, Colwill Karen, Gladwish Katharine, Muskat Brenda, Kinach Robert, Adams Sally-Lin, Moran Michael F, Morin Gregg B, Topaloglou Thodoros, Figeys Daniel (2007). «Large-scale mapping of human protein-protein interactions by mass spectrometry». Mol. Syst. Biol. (England) 3: 89. PMID 17353931. doi:10.1038/msb4100134.
Lu Q, Pallas DC, Surks HK, Baur WE, Mendelsohn ME, Karas RH (2004). «Striatin assembles a membrane signaling complex necessary for rapid, nongenomic activation of endothelial NO synthase by estrogen receptor alpha». Proc. Natl. Acad. Sci. U.S.A. 101 (49): 17126-31. PMC 534607. PMID 15569929. doi:10.1073/pnas.0407492101.

Datos: Q18031768

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[pmid9693043-1] Moqrich A, Mattei MG, Bartoli M, Rakitina T, Baillat G, Monneron A, Castets F (Sep de 1998). «Cloning of human striatin cDNA (STRN), gene mapping to 2p22-p21, and preferential expression in brain». Genomics 51 (1): 136-9. PMID 9693043. doi:10.1006/geno.1998.5342.

[pmid8769426-2] Castets F, Bartoli M, Barnier JV, Baillat G, Salin P, Moqrich A, Bourgeois JP, Denizot F, Rougon G, Calothy G, Monneron A (Oct de 1996). «A novel calmodulin-binding protein, belonging to the WD-repeat family, is localized in dendrites of a subset of CNS neurons». J Cell Biol 134 (4): 1051-62. PMC 2120968. PMID 8769426.

[entrez-3] «Entrez Gene: STRN striatin, calmodulin binding protein».

[pmid18782753-4] Goudreault, Marilyn; D'Ambrosio Lisa M, Kean Michelle J, Mullin Michael J, Larsen Brett G, Sanchez Amy, Chaudhry Sidharth, Chen Ginny I, Sicheri Frank, Nesvizhskii Alexey I, Aebersold Ruedi, Raught Brian, Gingras Anne-Claude (Jan. de 2009). «A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein». Mol. Cell Proteomics (United States) 8 (1): 157-71. PMID 18782753. doi:10.1074/mcp.M800266-MCP200.

[pmid17353931-5] Ewing, Rob M; Chu Peter, Elisma Fred, Li Hongyan, Taylor Paul, Climie Shane, McBroom-Cerajewski Linda, Robinson Mark D, O'Connor Liam, Li Michael, Taylor Rod, Dharsee Moyez, Ho Yuen, Heilbut Adrian, Moore Lynda, Zhang Shudong, Ornatsky Olga, Bukhman Yury V, Ethier Martin, Sheng Yinglun, Vasilescu Julian, Abu-Farha Mohamed, Lambert Jean-Philippe, Duewel Henry S, Stewart Ian I, Kuehl Bonnie, Hogue Kelly, Colwill Karen, Gladwish Katharine, Muskat Brenda, Kinach Robert, Adams Sally-Lin, Moran Michael F, Morin Gregg B, Topaloglou Thodoros, Figeys Daniel (2007). «Large-scale mapping of human protein-protein interactions by mass spectrometry». Mol. Syst. Biol. (England) 3: 89. PMID 17353931. doi:10.1038/msb4100134.

[pmid15569929-6] Lu Q, Pallas DC, Surks HK, Baur WE, Mendelsohn ME, Karas RH (2004). «Striatin assembles a membrane signaling complex necessary for rapid, nongenomic activation of endothelial NO synthase by estrogen receptor alpha». Proc. Natl. Acad. Sci. U.S.A. 101 (49): 17126-31. PMC 534607. PMID 15569929. doi:10.1073/pnas.0407492101.