necrosis

(noun)

The localized death of cells or tissues through injury, disease, or the interruption of blood supply.

Related Terms

Examples of necrosis in the following topics:

  • The Complement System and Heart Disease

    • The process is aided by neutrophils, the complement system, and tumor necrosis factor alpha.

  • Fusobacteria

    • The diseases attributed to Fusobacterium infection involve symptoms that include tissue necrosis, septicemia, intra-amniotic infections and ulcers.

  • Lymphogranuloma Venereum

    • These changes can further progress to necrosis, abscesses and fistulas.

  • Gangrene

    • The primary cause of gangrene is reduced blood supply to the affected tissues, which results in necrosis, or cell death.

  • Immune Complex Autoimmune Reactions

    • Further aggregation of immune complex-related processes induces a local fibrinoid necrosis with ischemia-aggravating thrombosis in the tissue vessel walls.

  • Bacterial Skin Diseases

    • More severe infections can result in vesicles, bullae, and petechiae, with possible skin necrosis.

  • Type III (Immune Complex) Reactions

    • As observed under methods of histopathology, acute necrotizing vasculitis within the affected tissues is observed concomitant to neutrophilic infiltration, along with notable eosinophilic deposition (fibrinoid necrosis).