Pulvinar nuclei

pulvinar nuclei
Hind- and mid-brains; postero-lateral view. (Pulvinar visible near top.)
Thalamic nuclei:
MNG = Midline nuclear group
AN = Anterior nuclear group
MD = Medial dorsal nucleus
VNG = Ventral nuclear group
VA = Ventral anterior nucleus
VL = Ventral lateral nucleus
VPL = Ventral posterolateral nucleus
VPM = Ventral posteromedial nucleus
LNG = Lateral nuclear group
PUL = Pulvinar
MTh = Metathalamus
LG = Lateral geniculate nucleus
MG = Medial geniculate nucleus
Details
Part ofthalamus
Identifiers
Latinnuclei pulvinares (the nuclei plurally); pulvinar thalami (the set of nuclei singularly)
MeSHD020649
NeuroNames328
NeuroLex IDbirnlex_824
TA98A14.1.08.104
A14.1.08.610
TA25665, 5698
FMA62178
Anatomical terms of neuroanatomy

The pulvinar nuclei or nuclei of the pulvinar (nuclei pulvinares) are the nuclei (cell bodies of neurons) located in the thalamus (a part of the vertebrate brain). As a group they make up the collection called the pulvinar of the thalamus (pulvinar thalami), usually just called the pulvinar.

The pulvinar is usually grouped as one of the lateral thalamic nuclei in rodents and carnivores, and stands as an independent complex in primates.

Structure

By convention, the pulvinar is divided into four nuclei:

TA alphanumeric identifierTA nameEnglish translation
A14.1.08.611nucleus pulvinaris anterioranterior pulvinar nucleus
A14.1.08.612nucleus pulvinaris inferiorinferior pulvinar nucleus
A14.1.08.613nucleus pulvinaris lateralislateral pulvinar nucleus
A14.1.08.614nucleus pulvinaris medialismedial pulvinar nucleus

Their connectomic details are as follows:

Clinical significance

Lesions of the pulvinar can result in neglect syndromes and attentional deficits.[6] In addition, lesions in early life can impact normal visuomotor behaviors such as reaching and grasping.[7] Furthermore, the pulvinar was demonstrated to be instrumental in the preservation of vision afforded to a boy who lost his primary visual cortex bilaterally at birth[8] as well as other forms of blindsight in monkeys[9][10] and humans.[11] Strokes affecting the pulvinar have also been implicated in the development of chronic pain.[12]

Other animals

The pulvinar varies in importance in different animals: it is virtually nonexistent in the rat, and grouped as the lateral posterior-pulvinar complex with the lateral posterior thalamic nucleus due to its small size in cats. In humans it makes up roughly 40% of the thalamus making it the largest of its nuclei.[13] Significant research has been undertaken in the marmoset examining the role of the retinorecipient region of the inferior pulvinar (medial subdivision), which projects to visual cortical area MT, in the early development of MT and the dorsal stream, as well as following early-life lesions of the primary visual cortex (V1).[14][15][16]

Etymology and pronunciation

The word pulvinar (/pʌlˈvaɪnər/) comes to scientific English vocabulary via New Latin from classical Latin pulvinus 'cushion'. In the religion of ancient Rome, a pulvinar was an empty throne, a cushioned couch for occupation by a deity. Like the cervix uteri is usually just called the cervix (with "which cervix" being implicit), the pulvinar thalami (pulvinar of the thalamus) is usually just called the pulvinar; no other anatomic structure in today's Terminologia Anatomica is called a pulvinar,[17] although in older terminology a part of the glomus body was called the pulvinar tunicae internae segmenti arterialis anastomosis arteriovenae glomeriformis. Each pulvinar nucleus (nucleus pulvinaris) has its own set of cortical connections.

References

  1. ↑ Cappe C.; Morel A.; Barone P.; Rouiller E.M. (2009). "The thalamocortical projection systems in primate: an anatomical support for multisensory and sensorimotor interplay". Cerebral Cortex. 19 (9): 2025–2037. doi:10.1093/cercor/bhn228. PMC 2722423. PMID 19150924.
  2. ↑ Berman R.; Wurtz R. (2011). "Signals conveyed in the pulvinar pathway from superior colliculus to cortical area mt". The Journal of Neuroscience. 31 (2): 373–384. doi:10.1523/jneurosci.4738-10.2011. PMC 6623455. PMID 21228149.
  3. ↑ Robinson D.; Petersen S. (1985). "Responses of pulvinar neurons to real and self-induced stimulus movement". Brain Research. 338 (2): 392–394. doi:10.1016/0006-8993(85)90176-3. PMID 4027606. S2CID 7547426.
  4. ↑ Petersen S.; Robinson D.; Morris J. (1987). "Contributions of the pulvinar to visual spatial attention". Neuropsychologia. 25 (1): 97–105. doi:10.1016/0028-3932(87)90046-7. PMID 3574654. S2CID 23143322.
  5. ↑ Chalupa, L. (1991). Visual function of the pulvinar. The Neural Basis of Visual Function. CRC Press, Boca Raton, Florida, pp. 140-159.
  6. ↑ Arend I.; Rafal R.; Ward R. (2008). "Spatial and temporal deficits are regionally dissociable in patients with pulvinar lesions". Brain. 131 (8): 2140–2152. doi:10.1093/brain/awn135. PMID 18669494.
  7. ↑ Mundinano, Inaki (2018). "Transient visual pathway critical for normal development of primate grasping behavior". Proceedings of the National Academy of Sciences. 115 (6): 1364–1369. doi:10.1073/pnas.1717016115. PMC 5819431. PMID 29298912.
  8. ↑ Mundinano, IC; Chen, J; de Souza, M; Sarossy, MG; Joanisse, MF; Goodale, MA; Bourne, JA (2017). "More than blindsight: Case report of a child with extraordinary visual capacity following perinatal bilateral occipital lobe injury". Neuropsychologia. 128: 178–186. doi:10.1016/j.neuropsychologia.2017.11.017. PMID 29146465. S2CID 207242249.
  9. ↑ Kinoshita M, Kato R, Isa K, Kobayashi K, Kobayashi K, Onoe H, Isa T (2019-01-11). "Dissecting the circuit for blindsight to reveal the critical role of pulvinar and superior colliculus". Nat Commun. doi:10.1038/s41467-018-08058-0. PMID 30635570.
  10. ↑ Takakuwa N, Isa K, Onoe H, Takahashi J, Isa T (2021-02-24). "Contribution of the Pulvinar and Lateral Geniculate Nucleus to the Control of Visually Guided Saccades in Blindsight Monkeys". J Neurosci. doi:10.1523/JNEUROSCI.2293-20.2020. PMID 33443074.
  11. ↑ Kletenik I, Ferguson MA, Bateman JR, Cohen AL, Lin C, Tetreault A, Pelak VS, Anderson CA, Prasad S, Darby RR, Fox MD (2021-12-27). "Network Localization of Unconscious Visual Perception in Blindsight". Annals of Neurology. doi:10.1002/ana.26292. PMID 34961965.
  12. ↑ Vartiainen, Nuutti; Perchet, Caroline; Magnin, Michel; Creac’h, Christelle; Convers, Philippe; Nighoghossian, Norbert; Mauguière, François; Peyron, Roland; Garcia-Larrea, Luis (March 2016). "Thalamic pain: anatomical and physiological indices of prediction". Brain. 139 (3): 708–722. doi:10.1093/brain/awv389. ISSN 0006-8950. PMID 26912644.
  13. ↑ LaBerge, D. (1999). Attention pp. 44-98. In Cognitive science (Handbook of Perception and Cognition, Second Edition), Bly BM, Rumelhart DE. (edits). Academic Press ISBN 978-0-12-601730-4 p. 73
  14. ↑ Warner CE, Kwan WC, Bourne JA (2012). "The early maturation of visual cortical area MT is dependent on input from the retinorecipient medial portion of the inferior pulvinar". Journal of Neuroscience. 32 (48): 17073–17085. doi:10.1523/JNEUROSCI.3269-12.2012. PMC 6621860. PMID 23197701.
  15. ↑ Warner CE, Goldshmit Y, Bourne JA (2010). "Retinal afferents synapse with relay cells targeting the middle temporal area in the pulvinar and lateral geniculate nuclei". Front Neuroanat. 4: 8. doi:10.3389/neuro.05.008.2010. PMC 2826187. PMID 20179789.
  16. ↑ Warner CE, Kwan WC, Wright D, Johnston LA, Egan GF, Bourne JA (2015). "Preservation of vision by the pulvinar following early-life primary visual cortex lesions". Curr Biol. 25 (4): 424–434. doi:10.1016/j.cub.2014.12.028. PMID 25601551.
  17. ↑ Baud, RH; et al., "Latin index of TA98, Terminologia Anatomica version 1998", Federative International Programme on Anatomical Terminologies (FIPAT), International Federation of Associations of Anatomists (IFAA), hosted by the University of Fribourg (Switzerland)

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