TachoSil
| Combination of | |
|---|---|
| Fibrinogen | Glycoprotein |
| Thrombin | Coagulation factor |
| Clinical data | |
| Trade names | TachoSil |
| AHFS/Drugs.com | Professional Drug Facts |
| Routes of administration | Epilesional |
| ATC code | |
| Legal status | |
| Legal status | |
| Identifiers | |
| CAS Number | |
| DrugBank | |
| UNII | |
TachoSil is a collagen sponge coated with the human coagulation factors fibrinogen and thrombin.[3] It is used during surgery to stop local bleeding on internal organs (hemostasis). The sponge is manufactured from horse tendons. TachoSil reacts upon contact with blood, other body fluids or saline to form a clot that glues it to the tissue surface. Hemostasis is reached in a few minutes, and the sponge is absorbed by the body within several weeks.
Some patients experience hypersensitivity or allergic reactions. In rare cases, it could turn into severe hypersensitive reaction. Those who are prone to having a systemic reaction to horse proteins or human blood products are not good candidates for use of TachoSil.
See also
References
- ↑ "TachoSil sealant matrix - Summary of Product Characteristics (SmPC)". (emc). 31 January 2020. Retrieved 9 July 2020.
- ↑ "TachoSil EPAR". European Medicines Agency (EMA). 17 September 2018. Retrieved 9 July 2020.
- ↑ Colombo GL, Bettoni D, Di Matteo S, Grumi C, Molon C, Spinelli D, Mauro G, Tarozzo A, Bruno GM (2014). "Economic and outcomes consequences of TachoSil®: a systematic review". Vascular Health and Risk Management. 10: 569–75. doi:10.2147/VHRM.S63199. PMC 4166367. PMID 25246797.
External links
- "TachoSil". Drug Information Portal. U.S. National Library of Medicine.
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