Desmethylmoramide
Desmethylmoramide (INN) is an opioid analgesic related to dextromoramide (the active (+)-isomer of moramide) that was synthesized and characterized in the late 1950s but was never marketed.[1][2][3]
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Preferred IUPAC name
4-(Morpholin-4-yl)-2,2-diphenyl-1-(pyrrolidin-1-yl)butan-1-one | |
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Properties | |
C24H30N2O2 | |
Molar mass | 378.516 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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See also
References
- Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 363–. ISBN 978-1-4757-2085-3.
- Morton IK, Hall JM (6 December 2012). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. pp. 94–. ISBN 978-94-011-4439-1.
- Janssen PA, Jageneau AH (June 1957). "A new series of potent analgesics: dextro 2:2-diphenyl-3-methyl-4-morpholino-butyrylpyrrolidine and related amides. I. Chemical structure and pharmacological activity". The Journal of Pharmacy and Pharmacology. 9 (6): 381–400. doi:10.1111/j.2042-7158.1957.tb12290.x. PMID 13439527. S2CID 58956931.
Further reading
- Davis MA, Winthrop SO, Stewart J, Sunahara FA, Herr F (May 1963). "New Psychotropic Agents. V. Derivatives of 5-Cyano- and 5-Carboxamidodibenzo[a,d]cycloheptadiene". Journal of Medicinal Chemistry. 6 (3): 251–255. doi:10.1021/jm00339a008. PMID 14185978.
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