Ammonium lactate

Ammonium lactate is a compound with formula NH4(C2H4(OH)COO). It is the ammonium salt of lactic acid. It has mild anti-bacterial properties.

Ammonium lactate
Structural formulae of the constituent ions
Ball-and-stick model of the lactate anion
Ball-and-stick model of the lactate anion
Ball-and-stick model of the ammonium cation
Ball-and-stick model of the ammonium cation
Names
IUPAC name
azanium 2-hydroxypropanoate
Other names
Ammonium lactate
Lac-hydrin
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.007.469
E number E328 (antioxidants, ...)
UNII
  • InChI=1S/C3H6O3.H3N/c1-2(4)3(5)6;/h2,4H,1H3,(H,5,6);1H3 ☒N
    Key: RZOBLYBZQXQGFY-UHFFFAOYSA-N ☒N
  • InChI=1/C3H6O3.H3N/c1-2(4)3(5)6;/h2,4H,1H3,(H,5,6);1H3
    Key: RZOBLYBZQXQGFY-UHFFFAOYAD
  • CC(C(=O)[O-])O.[NH4+]
Properties
C3H9O3N
Molar mass 107.06 g/mol
Pharmacology
QA16QA04 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)
Infobox references

It has E number "E328" and is the active ingredient of the skin lotions Amlactin and Lac-Hydrin.[1]

Ammonium lactate is the chemical combination of lactic acid and ammonium hydroxide. It is used as a skin moisturizer lotion to treat dry, scaly, itchy skin. Those who are using it should avoid exposure to sunlight or artificial UV rays, such as sunlamps or tanning beds. Ammonium lactate makes skin more sensitive to sunlight, and skin is more likely to sunburn.

Ammonium lactate is sold as an over-the-counter medication Amlactin brand used for treating xerosis.[2][3]

References
  1. "DailyMed: View Drug Label: Lac-Hydrin (ammonium lactate) Lotion". Lac-Hydrin specially formulates 12% lactic acid, neutralized with ammonium hydroxide, as ammonium lactate to provide a lotion pH of 4.4-5.5. ... Lactic acid is an alpha-hydroxy acid. It is a normal constituent of tissues and blood. The alpha-hydroxy acids (and their salts) may act as humectants when applied to the skin.
  2. "Why Lactic Acid?". Advantice Health, LLC. Retrieved July 27, 2023.
  3. Draelos, Z. D.; Hall, S.; Munsick, C. (2020). "A 14-day Controlled Study Assessing Qualitative Improvement with 15% Lactic Acid and Ceramides in Skin Moisturization and Desquamation". The Journal of Clinical and Aesthetic Dermatology. 13 (8): E54–E58. PMC 7595367. PMID 33178384.


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