GNG3

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 is a protein that in humans is encoded by the GNG3 gene.[5][6]

GNG3
Identifiers
AliasesGNG3, G protein subunit gamma 3, HG3D
External IDsOMIM: 608941 MGI: 102704 HomoloGene: 22575 GeneCards: GNG3
Orthologs
SpeciesHumanMouse
Entrez

2785

14704

Ensembl

ENSG00000162188

ENSMUSG00000071658

UniProt

P63215

P63216

RefSeq (mRNA)

NM_012202

NM_010316

RefSeq (protein)

NP_036334

NP_034446

Location (UCSC)Chr 11: 62.71 – 62.71 MbChr 19: 8.81 – 8.82 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

G proteins are heterotrimers of alpha, beta, and gamma subunits. Gamma subunits, such as GNG3, contribute to the specificity of the hundreds of receptor signaling pathways involving G proteins (Schwindinger et al., 2004).[supplied by OMIM][6]

References

  1. GRCh38: Ensembl release 89: ENSG00000162188 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000071658 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Downes GB, Gautam N (Mar 2000). "The G protein subunit gene families". Genomics. 62 (3): 544–52. doi:10.1006/geno.1999.5992. PMID 10644457.
  6. "Entrez Gene: GNG3 guanine nucleotide binding protein (G protein), gamma 3".

Further reading



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