Progoitrin

Progoitrin is a biochemical from the glucosinolate family that is found in some food, which is inactive but after ingestion is converted to goitrin. Goitrin decreases the thyroid hormone production.

Progoitrin
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
KEGG
UNII
  • InChI=1S/C11H19NO10S2/c1-2-5(14)3-7(12-22-24(18,19)20)23-11-10(17)9(16)8(15)6(4-13)21-11/h2,5-6,8-11,13-17H,1,3-4H2,(H,18,19,20)/t5-,6+,8+,9-,10+,11-/m0/s1
    Key: MYHSVHWQEVDFQT-ILPXZUKPSA-N
  • OC[C@H]1O[C@@H](SC(C[C@@H](O)C=C)=NOS(O)(=O)=O)[C@H](O)[C@@H](O)[C@@H]1O
Properties
C11H19NO10S2
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Progoitrin has been isolated in cabbage, brussels sprouts, kale, peanuts, mustard, rutabaga, kohlrabi, spinach, cauliflower, horseradish, and rapeseed oil.[1]

References
  1. Comprehensive Pharmacy Review, Leon Shargel, 6th edition, p1191.

Bibliography
  • Greer, Monte A. (20 March 1956). "Isolation from Rutabaga Seed of Progoitrin, the Precursor of the Naturally Occurring Antithyroid Compound, Goitrin (L-5-Vinyl-2-Thioöxazolidine)1". Journal of the American Chemical Society. 78 (6): 1260–1261. doi:10.1021/ja01587a052.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.