Blosozumab

Blosozumab binds SOST, a negative regulator of osteoblast activity. Blocking SOST activity can lead to increased bone density.[1] Blosozaumab has been studied with regards to the treatment of osteoporosis in both men and postmenopausal women. Clinical trials with Blosozumab have shown the antibody to be well tolerated and effective in producing a bone anabolic effect.[2]

Blosozumab
Monoclonal antibody
TypeWhole antibody
SourceHumanized (from mouse)
TargetSOST
Clinical data
ATC code
  • none
Identifiers
CAS Number
ChemSpider
  • none
UNII
KEGG
Chemical and physical data
FormulaC6462H9852N1684O2030S46
Molar mass145086.42 g·mol−1
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Blosozumab was developed by Eli Lilly and Company.

References

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