Ceronapril

Ceronapril (INN,[1] proposed trade names Ceranapril, Novopril) in a phosphonate ACE inhibitor[2] that was never marketed.

Ceronapril
Clinical data
AHFS/Drugs.comMonograph
ATC code
Identifiers
IUPAC name
  • 1-[(2S)-6-Amino-2-hydroxyhexanoyl]-L-proline, hydrogen (4-phenyl-butyl)phosphonate
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC30H46NO7P
Molar mass563.672 g·mol−1
3D model (JSmol)
SMILES
  • C1C[C@H](N(C1)C(=O)[C@H](CCCCN)OP(=O)(CCCCC2=CC=CC=C2)O)C(=O)O
InChI
  • InChI=1S/C30H46NO7P/c1-4-28(33)37-30(22(2)3)38-39(36,18-12-11-15-23-13-7-5-8-14-23)21-27(32)31-20-25(19-26(31)29(34)35)24-16-9-6-10-17-24/h5,7-8,13-14,22,24-26,30H,4,6,9-12,15-21H2,1-3H3,(H,34,35)/t25-,26+,30?,39-/m1/s1 Y
  • Key:BIDNLKIUORFRQP-YYTCENNOSA-N Y

References
  1. "International Nonproprietary Names for Pharmaceutical Substances (INN). Recommended International Nonproprietary Names (Rec. INN): List 31" (PDF). World Health Organization. p. 4. Retrieved 2 March 2017.
  2. Tu JI, Brennan J, Stouffer B, Mantha S, Turabi N, Tsay HM (June 1992). "Radioimmunoassay for ceronapril, a new angiotensin-converting enzyme inhibitor, and its application to a pharmacokinetic study in healthy male volunteers". Therapeutic Drug Monitoring. 14 (3): 209–19. doi:10.1097/00007691-199206000-00007. PMID 1412607. S2CID 23854785.
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