Co-tenidone

Co-tenidone (BAN) is a non-proprietary name used to denote a combination of atenolol and chlortalidone. Co-tenidone is used in the treatment of hypertension. The use of β-blockers in hypertension was downgraded in June 2006 in the United Kingdom to fourth-line because they perform less well than other drugs, and because atenolol, the most frequently used β-blocker, at usual doses carries an unacceptable risk of provoking type 2 diabetes.[1]

Co-tenidone
Combination of
AtenololBeta blocker
ChlortalidoneThiazide diuretic
Clinical data
Routes of
administration		Oral
Legal status
Legal status
  • UK: POM (Prescription only)
Identifiers
ChemSpider
  (verify)

Formulation

Two strengths of co-tenidone are currently available in the UK:

  • 50 mg atenolol and 12.5 mg chlortalidone, BAN of Co-tenidone 50/12.5
  • 100 mg atenolol and 25 mg chlortalidone, BAN of Co-tenidone 100/25

References
  • British National Formulary 54, September 2007

Footnotes
  1. Ladva S (2006-06-28). "NICE and BHS launch updated hypertension guideline". National Institute for Health and Clinical Excellence.
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