Bietaserpine

Bietaserpine (INN), or 1-[2-(diethylamino)ethyl]reserpine, is a derivative of reserpine used as an antihypertensive agent. Like reserpine, bietaserpine is a VMAT inhibitor.[1]

Bietaserpine
Names
Preferred IUPAC name
Methyl (1S,2R,3R,4aS,13bR,14aS)-13-[2-(diethylamino)ethyl]-2,11-dimethoxy-3-(3,4,5-trimethoxybenzoyl)-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroindolo[2′,3′:3,4]pyrido[1,2-b]isoquinoline-1-carboxylate
Identifiers
CAS Number
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.000.151
PubChem CID
UNII
InChI
  • InChI=1S/C39H53N3O9/c1-9-40(10-2)15-16-42-29-20-25(45-3)11-12-26(29)27-13-14-41-22-24-19-33(37(49-7)34(39(44)50-8)28(24)21-30(41)35(27)42)51-38(43)23-17-31(46-4)36(48-6)32(18-23)47-5/h11-12,17-18,20,24,28,30,33-34,37H,9-10,13-16,19,21-22H2,1-8H3/t24-,28+,30-,33-,34+,37+/m1/s1 Y
    Key: WFTSRDISOMSAQC-ZNFOTRSXSA-N Y
SMILES
  • COc1cc(cc(OC)c1OC)C(=O)O[C@@H]4C[C@@H]5CN6CCc3c(n(CCN(CC)CC)c2cc(OC)ccc23)[C@H]6C[C@@H]5[C@H](C(=O)OC)[C@H]4OC
Properties
Chemical formula
 C39H53N3O9
Molar mass 707.865 g·mol−1
Pharmacology
C02AA07 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

References
  1. Buckingham J et al. (eds.) (1993). Dictionary of Natural Products, vol. 5, p. 4923, Boca Raton: Chapman & Hall/CRC. ISBN 978-0-412-46620-5. Retrieved on June 22, 2009 through Google Book Search.


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