RTI-353
RTI(-4229)-353 is a phenyltropane derived drug which acts as an SSRI.[1] Tamagnan et al. also made some phenyltropanes with high activity and selectivity for the SERT (pM affinity).[2]
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Formula | C17H22INO2 |
Molar mass | 399.272 g·mol−1 |
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References
- Navarro HA, Xu H, Zhong D, Blough BE, Ross WP, Kuhar MJ, Carroll FI (September 2001). "[(125)I]3beta-(4-ethyl-3-iodophenyl)nortropane-2beta-carboxylic acid methyl ester ([(125)I]EINT): a potent and selective radioligand for the brain serotonin transporter". Synapse. New York, N.Y. 41 (3): 241–7. doi:10.1002/syn.1081. PMID 11418937. S2CID 2323766.
- Tamagnan G, Alagille D, Fu X, Kula NS, Baldessarini RJ, Innis RB, Baldwin RM (January 2006). "Synthesis and monoamine transporter affinity of new 2beta-carbomethoxy-3beta-[aryl or heteroaryl]phenyltropanes". Bioorganic & Medicinal Chemistry Letters. 16 (1): 217–20. doi:10.1016/j.bmcl.2005.09.016. PMID 16236497.
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