Eclanamine

Eclanamine (U-48,753) is a drug which was patented as an antidepressant, but was never marketed.[1] It acts by inhibiting the reuptake of serotonin and norepinephrine.[2]

Eclanamine
Clinical data
ATC code
  • None
Identifiers
IUPAC name
  • N-(3,4-dichlorophenyl)-N-[(1R,2R)-2-(dimethylamino)cyclopentyl]propanamide
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC16H22Cl2N2O
Molar mass329.27 g·mol−1
3D model (JSmol)
SMILES
  • Clc2ccc(N(C(=O)CC)[C@@H]1CCC[C@H]1N(C)C)cc2Cl
InChI
  • InChI=1S/C16H22Cl2N2O/c1-4-16(21)20(11-8-9-12(17)13(18)10-11)15-7-5-6-14(15)19(2)3/h8-10,14-15H,4-7H2,1-3H3/t14-,15-/m1/s1
  • Key:YCRFSKUCDBJWLX-HUUCEWRRSA-N

See also

References
  1. Triggle DJ (1997). Dictionary of pharmacological agents. London: Chapman & Hall. ISBN 978-0-412-46630-4.
  2. Rees DC (1992). "Chemical structures and biological activities of non-peptide selective kappa opioid ligands". Progress in Medicinal Chemistry. 29: 109–39 (128). doi:10.1016/s0079-6468(08)70006-7. ISBN 978-0-444-89472-4. PMID 1335584.
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