Etybenzatropine

Etybenzatropine (INN), also known as ethybenztropine (USAN, BAN) and tropethydrylin, is an anticholinergic/antihistamine marketed under the trade names Panolid, Ponalid, and Ponalide, which is used as an antiparkinsonian agent.[1] Like its analogue benzatropine, it may act as a dopamine reuptake inhibitor.

Etybenzatropine
Clinical data
Routes of
administration
Oral, IM, IV
ATC code
Identifiers
IUPAC name
  • (3-endo)-3-(Diphenylmethoxy)-8-ethyl-8-azabicyclo[3.2.1]octane
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC22H27NO
Molar mass321.464 g·mol−1
3D model (JSmol)
SMILES
  • CCN1[C@@H]2CC[C@H]1C[C@H](C2)OC(c3ccccc3)c4ccccc4
InChI
  • InChI=1S/C22H27NO/c1-2-23-19-13-14-20(23)16-21(15-19)24-22(17-9-5-3-6-10-17)18-11-7-4-8-12-18/h3-12,19-22H,2,13-16H2,1H3/t19-,20+,21+ Y
  • Key:PHTMLLGDZBZXMW-AERCQKQUSA-N Y
  (verify)

See also

References

  1. Pourcher E, Bonnet AM, Kefalos J, Dubois B, Agid Y (1989). "Effects of etybenzatropine and diazepam on levodopa-induced diphasic dyskinesias in Parkinson's disease". Movement Disorders. 4 (3): 195–201. doi:10.1002/mds.870040301. PMID 2779590.


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