Etodroxizine

Etodroxizine (INN) (brand names Vesparax, Drimyl, Indunox, Isonox) is a first-generation antihistamine of the diphenylmethylpiperazine group which is used as a sedative/hypnotic drug in Europe and South Africa.[1][2][3][4]

Etodroxizine
Clinical data
ATC code
  • None
Identifiers
IUPAC name
  • 2-[2-(2-{4-[(4-Chlorophenyl)(phenyl)methyl]-1-piperazinyl}ethoxy)ethoxy]ethanol
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
Chemical and physical data
FormulaC23H31ClN2O3
Molar mass418.96 g·mol−1
3D model (JSmol)
SMILES
  • c1ccc(cc1)C(c2ccc(cc2)Cl)N3CCN(CC3)CCOCCOCCO
InChI
  • InChI=1S/C23H31ClN2O3/c24-22-8-6-21(7-9-22)23(20-4-2-1-3-5-20)26-12-10-25(11-13-26)14-16-28-18-19-29-17-15-27/h1-9,23,27H,10-19H2
  • Key:VUFOCTSXHUWGPW-UHFFFAOYSA-N

See also

References
  1. Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000. pp. 418–. ISBN 978-3-88763-075-1.
  2. William Andrew Publishing (22 October 2013). Pharmaceutical Manufacturing Encyclopedia, 3rd Edition. Elsevier. pp. 1525–. ISBN 978-0-8155-1856-3.
  3. Wolffgramm J, Lechner J, Coper H (1988). "Interaction of two barbiturates and an antihistamine on body temperature and motor performance of mice". Arzneimittelforschung. 38 (7): 885–91. PMID 2905131.
  4. Maurer H, Pfleger K (1988). "Identification and differentiation of alkylamine antihistamines and their metabolites in urine by computerized gas chromatography-mass spectrometry". J Chromatogr. 430 (1): 31–41. doi:10.1016/s0378-4347(00)83131-x. PMID 2905706.


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