Dichloralphenazone

Dichloralphenazone is a 1:2 mixture of antipyrine with chloral hydrate. In combination with paracetamol and isometheptene, it is the active ingredient of medications for migraine and tension headaches, including Epidrin and Midrin. Performance impairments are common with this drug and caution is advised, for example when driving motor vehicles. Additional uses of dichloralphenazone include sedation for the treatment of short-term insomnia, although there are probably better drug choices for the treatment of insomnia.[1]

Dichloralphenazone
Combination of
PhenazoneAnalgesic
Chloral hydrateSedative
Clinical data
MedlinePlusa601064
Routes of
administration		Oral
ATC code
Legal status
Legal status
  • US: Schedule IV
Identifiers
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard100.006.861
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See also

References
  1. Hindmarch I, Parrott AC (1980). "The effects of combined sedative and anxiolytic preparations on subjective aspects of sleep and objective measures of arousal and performance the morning following nocturnal medication. I: Acute doses". Arzneimittel-Forschung. 30 (6): 1025–8. PMID 6106498.
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