Hydroxyphenamate

Hydroxyphenamate or oxyfenamate (trade name Listica) is a sedative and anxiolytic drug of the carbamate class which is no longer marketed in the US. Like other carbamate sedatives, it is chemically related to meprobamate (Miltown). It was introduced to the US market in 1961. The dosage for adults is 200 mg 3 to 4 times daily.[1]

Hydroxyphenamate
Clinical data
Trade namesListica
Identifiers
IUPAC name
  • (2-hydroxy-2-phenylbutyl) carbamate
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
ECHA InfoCard100.000.016
Chemical and physical data
FormulaC11H15NO3
Molar mass209.245 g·mol−1
3D model (JSmol)
SMILES
  • CCC(COC(=O)N)(C1=CC=CC=C1)O
InChI
  • InChI=1S/C11H15NO3/c1-2-11(14,8-15-10(12)13)9-6-4-3-5-7-9/h3-7,14H,2,8H2,1H3,(H2,12,13)
  • Key:WAFIYOULDIWAKR-UHFFFAOYSA-N

References
  1. American Medical Association Dept of Drugs (1977). AMA Drug Evaluations (3rd ed.). Littleton, Mass.: Pub. Sciences Group. p. N-61. ISBN 978-0-88416-175-2. OCLC 1024170745.
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