Methoxypropane

Methoxypropane, or methyl propyl ether, is an ether once used as a general anaesthetic.[1] It is a clear colorless flammable liquid with a boiling point of 38.8 °C.[2]

Methoxypropane
Names
Preferred IUPAC name
1-Methoxypropane
Other names
Propane, 1-methoxy-
methyl propyl ether
Metopryl
Neothyl
propane, 1-methoxy
methyl n-propyl ether
Identifiers
CAS Number
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.008.327
EC Number
  • 209-158-7
PubChem CID
RTECS number
  • KO2280000
UNII
UN number 2612
InChI
  • InChI=1S/C4H10O/c1-3-4-5-2/h3-4H2,1-2H3 Y
    Key: VNKYTQGIUYNRMY-UHFFFAOYSA-N Y
  • InChI=1/C4H10O/c1-3-4-5-2/h3-4H2,1-2H3
SMILES
  • O(CCC)C
Properties
Chemical formula
 C4H10O
Molar mass 74.12
Density 0.7356 g/cm3
Boiling point 38.8 °C (101.8 °F; 311.9 K)
Solubility in water
 30.5 g/L
Refractive index (nD)
 1.35837 (14.3 °C)
Viscosity 0.3064 cP (0.3 °C)
Pharmacology
inhalation
Hazards
NFPA 704 (fire diamond)
0
3
0
Flash point < −20 °C (−4 °F; 253 K)
Explosive limits 1.9-11.8
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

Marketed under the trade names Metopryl and Neothyl, methoxypropane was used as an alternative to diethyl ether because of its greater potency. Its use as an anaesthetic has since been supplanted by modern halogenated ethers which are much less flammable.

References
  1. White, Mary Louise T.; Shane, Sylvan M.; Krantz, John C., Jr. "Anesthesia. XXI. Propyl methyl ether as an inhalation anesthetic in man", Anesthesiology, (1946), 7, 663-7.
  2. Merck Index, 11th edition, 6031.


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