Cloxazolam

Cloxazolam is a benzodiazepine derivative that has anxiolytic, sedative, and anticonvulsant properties. [2] It is not widely used; [2] as of August 2018 it was marketed in Belgium, Luxembourg, Portugal, Brazil, and Japan.[1] In 2019, it has been retired from the Belgian market. [3]

Not to be confused with Sepazon or Sibazon, a brand name for diazepam in Russia).
Cloxazolam
Clinical data
Trade namesAkton, Cloxam, Clozal, Elum, Olcadil, and Sepazon[1]
AHFS/Drugs.comInternational Drug Names
Routes of
administration		Oral
ATC code
Legal status
Legal status
  • CA: Schedule IV
  • DE: Anlage III (Special prescription form required)
  • UK: Class C
  • US: Schedule IV
Pharmacokinetic data
MetabolismHepatic
Elimination half-life65 hours
ExcretionRenal
Identifiers
IUPAC name
  • 10-chloro-11b-(2-chlorophenyl)-2,3,5,7-tetrahydro-[1,3]oxazolo[3,2-d][1,4]benzodiazepin-6-one
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC17H14Cl2N2O2
Molar mass349.21 g·mol−1
3D model (JSmol)
SMILES
  • Clc1ccccc1C42OCCN2CC(=O)Nc3c4cc(Cl)cc3
InChI
  • InChI=1S/C17H14Cl2N2O2/c18-11-5-6-15-13(9-11)17(12-3-1-2-4-14(12)19)21(7-8-23-17)10-16(22)20-15/h1-6,9H,7-8,10H2,(H,20,22) Y
  • Key:ZIXNZOBDFKSQTC-UHFFFAOYSA-N Y
 NY (what is this?)  (verify)

See also

References
  1. "Cloxazolam International Brands". Drugs.com. Retrieved 13 August 2018.
  2. Stolerman IP, ed. (2010). "C: Cloxazolam". Encyclopedia of Psychopharmacology. Berlin: Springer-Verlag. ISBN 978-3-540-68706-1.
  3. "Bon à savoir". cbip.be. Retrieved 13 August 2018.
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