Difebarbamate

Difebarbamate (INN) is a tranquilizer of the barbiturate and carbamate families which is used in Europe as a component of a combination drug formulation referred to as tetrabamate (Atrium, Sevrium).[1][2][3]

Difebarbamate
Clinical data
Routes of
administration		Oral
ATC code
  • None
Identifiers
IUPAC name
  • (5-ethyl-2,4,6-trioxo-5-phenyldihydropyrimidine-1,3(2H,4H)-diyl)bis-3-butoxypropane-1,2-diyl dicarbamate
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
ECHA InfoCard100.036.147
Chemical and physical data
FormulaC28H42N4O9
Molar mass578.663 g·mol−1
3D model (JSmol)
SMILES
  • O=C1N(C(=O)N(C(=O)C1(c2ccccc2)CC)CC(OC(=O)N)COCCCC)CC(OC(=O)N)COCCCC
InChI
  • InChI=1S/C28H42N4O9/c1-4-7-14-38-18-21(40-25(29)35)16-31-23(33)28(6-3,20-12-10-9-11-13-20)24(34)32(27(31)37)17-22(41-26(30)36)19-39-15-8-5-2/h9-13,21-22H,4-8,14-19H2,1-3H3,(H2,29,35)(H2,30,36)
  • Key:GJJRIOLBUILIGK-UHFFFAOYSA-N

See also

References
  1. Index nominum 2000: international drug directory. Taylor & Francis US. 2000. p. 333. ISBN 978-3-88763-075-1. Retrieved 26 November 2011.
  2. World Health Organization (2004). "The use of stems in the selection of International Nonproprietary Names (INN) for pharmaceutical substance" (PDF).
  3. Vachta J, Valter K, Siegfried B (1990). "Metabolism of difebarbamate in man". European Journal of Drug Metabolism and Pharmacokinetics. 15 (3): 191–8. doi:10.1007/BF03190203. PMID 2253648. S2CID 2916646.


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