Zapizolam

Zapizolam[1] is a pyridodiazepine drug, which is a benzodiazepine analog[2] of pyridotriazolodiazepine group. It has sedative and anxiolytic effects similar to those produced by benzodiazepine derivatives, and has been sold illicitly as a designer drug.[3]

Zapizolam
Clinical data
ATC code
  • none
Identifiers
IUPAC name
  • 8-Chloro-6-(2-chlorophenyl)-4H-pyrido[2,3-f][1,2,4]triazolo[4,3-a][1,4]diazepine
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
ECHA InfoCard100.058.774
Chemical and physical data
FormulaC15H9Cl2N5
Molar mass330.171 g·mol−1
3D model (JSmol)
SMILES
  • Clc4ccccc4C/3=N/Cc1nncn1c2c\3nc(Cl)cc2
InChI
  • InChI=1S/C15H9Cl2N5/c16-10-4-2-1-3-9(10)14-15-11(5-6-12(17)20-15)22-8-19-21-13(22)7-18-14/h1-6,8H,7H2 Y
  • Key:FOWABKOXWTZAKY-UHFFFAOYSA-N Y
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References
  1. DE Withdrawn 2649116, Von Bebenburg W, Schulmeyer N, Jakovlev V, "Neue 6-aryl-s-triazolo-(4,3-a)- pyrido-(2,3-f)-1,4-diazepine", published 18 May 1977, assigned to Evonik Operations GmbH
  2. "Chemical Book" (in Chinese).
  3. Zawilska JB, Wojcieszak J (July 2019). "An expanding world of new psychoactive substances-designer benzodiazepines". Neurotoxicology. 73: 8–16. doi:10.1016/j.neuro.2019.02.015. PMID 30802466.
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