Teflurane

Teflurane (INN, USAN, code name Abbott 16900) is a halocarbon drug which was investigated as an inhalational anesthetic but was never marketed.[1][2] Its clinical development was terminated due to a high incidence of cardiac arrhythmias in patients, similarly to the cases of halopropane and norflurane.[3]

Teflurane
Clinical data
ATC code
  • None
Identifiers
IUPAC name
  • 2-Bromo-1,1,1,2-tetrafluoroethane
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC2HBrF4
Molar mass180.928 g·mol−1
3D model (JSmol)
SMILES
  • C(C(F)(F)F)(F)Br
InChI
  • InChI=1S/C2HBrF4/c3-1(4)2(5,6)7/h1H
  • Key:RZXZIZDRFQFCTA-UHFFFAOYSA-N

Chemistry

Teflurane is 2-bromo-1,1,1,2-tetrafluoroethane, a haloalkane. It is a gas at standard conditions.[4] The compound is chiral.

See also

References
  1. Klein SL (1993). A glossary of anesthesia and related terminology. Springer-Verlag. ISBN 978-0-387-97831-4.
  2. Artusio JF, Mazzia VD (1962). Practical anesthesiology. Mosby. ISBN 9780608393322.
  3. Stanley TH, Petty WC (6 December 2012). Anesthesia, The Heart and the Vascular System: Annual Utah Postgraduate Course in Anesthesiology 1987. Springer Science & Business Media. pp. 185–. ISBN 978-94-009-3295-1.
  4. "2-Bromo-1,1,1,2-tetrafluoroethane". Chem Spider.


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