2C-B-PP

2,5-dimethoxy-4-bromophenylpiperazine (2C-B-PP) is a drug of the phenylpiperazine class. It acts as an agonist at serotonin receptors, and in studies on rats substituted for the psychedelic amphetamine derivative DOM with around 1/10 the potency but similar rates of stimulus-appropriate responding at the highest dose.[1][2]:867–868

2C-B-PP
Clinical data
ATC code
  • none
Identifiers
IUPAC name
  • 1-(2,5-dimethoxy-4-bromophenyl)piperazine
CAS Number
PubChem CID
UNII
ChEMBL
Chemical and physical data
FormulaC12H17BrN2O2
Molar mass301.184 g·mol−1
3D model (JSmol)
SMILES
  • COC1=CC(=C(C=C1N2CCNCC2)OC)Br
InChI
  • InChI=1S/C12H17BrN2O2/c1-16-11-8-10(12(17-2)7-9(11)13)15-5-3-14-4-6-15/h7-8,14H,3-6H2,1-2H3
  • Key:JLAQUWGWRNMYGA-UHFFFAOYSA-N

See also

References

  1. Lyon RA, Titeler M, McKenney JD, Magee PS, Glennon RA (May 1986). "Synthesis and evaluation of phenyl- and benzoylpiperazines as potential serotonergic agents". Journal of Medicinal Chemistry. 29 (5): 630–4. doi:10.1021/jm00155a008. PMID 3701781.
  2. Trachsel D, Lehmann D, Enzensperger C (2013). Phenethylamine: Von der Struktur zur Funktion. Nachtschatten Verlag AG. ISBN 978-3-03788-700-4.
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