Oxomemazine

Oxomemazine is an antihistamine and anticholinergic of the phenothiazine chemical class for the treatment of cough.[1][2]

Oxomemazine
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Legal status
Legal status
  • US: Not approved
  • In general: ℞ (Prescription only)
Identifiers
IUPAC name
  • 3-(5,5-Dioxido-10H-phenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.020.906
Chemical and physical data
FormulaC18H22N2O2S
Molar mass330.45 g·mol−1
3D model (JSmol)
SMILES
  • O=S3(=O)c1ccccc1N(c2c3cccc2)CC(C)CN(C)C
InChI
  • InChI=1S/C18H22N2O2S/c1-14(12-19(2)3)13-20-15-8-4-6-10-17(15)23(21,22)18-11-7-5-9-16(18)20/h4-11,14H,12-13H2,1-3H3 Y
  • Key:QTQPVLDZQVPLGV-UHFFFAOYSA-N Y
 NY (what is this?)  (verify)

This is the sulfoxide version of Trimeprazine.

Thieme Patent:[3]

See also

References
  1. Pujet JC, Keddad K, Sévenier F, Jolivet-Landreau I (2002). "[Comparative study of two antitussive drugs in the treatment of acute dry cough of infectious origin (prospective, randomized, single blind study)]". Therapie. 57 (5): 457–63. PMID 12611200.
  2. Lee SW, Woo CW, Kim JG (December 1994). "Selectivity of oxomemazine for the M1 muscarinic receptors". Archives of Pharmacal Research. 17 (6): 443–51. doi:10.1007/BF02979123. PMID 10319156. S2CID 34007107.
  3. Robert Michel Jacob, U.S. Patent 2,972,612 (1961 to Rhône-Poulenc).
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