Carpipramine

Carpipramine (Prazinil, Defekton) is an atypical antipsychotic used for the treatment of schizophrenia and anxiety in France and Japan.[1][2][3][4] In addition to its neuroleptic and anxiolytic effects, carpipramine also has hypnotic properties.[3] It is structurally related to both tricyclics like imipramine and butyrophenones like haloperidol.[3]

Carpipramine
Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration
Oral
ATC code
  • None
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
IUPAC name
  • 1-[3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl]-4-piperidin-1-ylpiperidine-4-carboxamide
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.025.182
Chemical and physical data
FormulaC28H38N4O
Molar mass446.639 g·mol−1
3D model (JSmol)
SMILES
  • O=C(N)C5(N1CCCCC1)CCN(CCCN4c2ccccc2CCc3ccccc34)CC5

See also

References

  1. Deniker P, Lôo H, Zarifian E, Verdeaux G, Garreau G (1977). "[A new psychotropic drug: carpipramine, intermediate compound between 2 therapeutic classes]". Encephale (in French). 3 (2): 133–48. PMID 19231.
  2. Pislová J, Pisl I, Petránová T, Petrová M (August 1974). "Clinical experience with carpipramine (Defekton)". Acta Nerv Super (Praha). 16 (3): 168–9. PMID 4608287.
  3. José Miguel Vela; Helmut Buschmann; Jörg Holenz; Antonio Párraga; Antoni Torrens (2007). Antidepressants, Antipsychotics, Anxiolytics: From Chemistry and Pharmacology to Clinical Application. Weinheim: Wiley-VCH. ISBN 978-3-527-31058-6.
  4. Swiss Pharmaceutical Society (2000). Index Nominum 2000: International Drug Directory (Book with CD-ROM). Boca Raton: Medpharm Scientific Publishers. ISBN 978-3-88763-075-1.
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