Quinazosin

Quinazosin is an antihypertensive α1-adrenergic receptor antagonist.[1]

Quinazosin
Names
Preferred IUPAC name
6,7-Dimethoxy-2-[4-(prop-2-en-1-yl)piperazin-1-yl]quinazolin-4-amine
Identifiers
CAS Number
3D model (JSmol)
ChemSpider
PubChem CID
UNII
InChI
  • InChI=1S/C17H23N5O2/c1-4-5-21-6-8-22(9-7-21)17-19-13-11-15(24-3)14(23-2)10-12(13)16(18)20-17/h4,10-11H,1,5-9H2,2-3H3,(H2,18,19,20)
    Key: HSIPLPKNLDWHSE-UHFFFAOYSA-N
  • InChI=1/C17H23N5O2/c1-4-5-21-6-8-22(9-7-21)17-19-13-11-15(24-3)14(23-2)10-12(13)16(18)20-17/h4,10-11H,1,5-9H2,2-3H3,(H2,18,19,20)
    Key: HSIPLPKNLDWHSE-UHFFFAOYAT
SMILES
  • COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)CC=C)N)OC
Properties
Chemical formula
 C17H23N5O2
Molar mass 329.404 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

References
  1. Martin, RA; Barsoum, NJ; Sturgess, JM; De La Iglesia, FA (1985). "Leukocyte and bone marrow effects of a thiomorpholine quinazosin antihypertensive agent". Toxicology and Applied Pharmacology. 81 (1): 166–73. doi:10.1016/0041-008x(85)90131-0. PMID 3840293.



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