Mabuterol

Mabuterol
Clinical data
Other names	Mabuterolum; PB 868Cl
Identifiers
	IUPAC name 1-[4-amino-3-chloro-5-(trifluoromethyl)phenyl]-2-(tert-butylamino)ethanol;
CAS Number	56341-08-3;
PubChem CID	3995;
ChemSpider	3857;
UNII	R4K19W6S7Q;
ChEBI	CHEBI:135325;
ChEMBL	ChEMBL86749;
CompTox Dashboard (EPA)	DTXSID3048283 ;
Chemical and physical data
Formula	C13H18ClF3N2O
Molar mass	310.75 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES Clc1cc(cc(c1N)C(F)(F)F)C(O)CNC(C)(C)C;
	InChI InChI=1S/C13H18ClF3N2O/c1-12(2,3)19-6-10(20)7-4-8(13(15,16)17)11(18)9(14)5-7/h4-5,10,19-20H,6,18H2,1-3H3; Key:JSJCTEKTBOKRST-UHFFFAOYSA-N;

Mabuterol is a selective β₂ adrenoreceptor agonist.[1][2]

References

Osada, E; Murai, T; Ishizaka, Y; Sanai, K (1984). "Pharmacological studies of mabuterol, a new selective beta 2-stimulant. II: Effects on the cardiovascular system and smooth muscle organs". Arzneimittel-Forschung. 34 (11A): 1641–51. PMID 6152157.
Akahane K, Furukawa Y, Ogiwara Y, Haniuda M, Chiba S (July 1989). "Beta-adrenoceptor blocking effects of a selective beta 2-agonist, mabuterol, on the isolated, blood-perfused right atrium of the dog". Br. J. Pharmacol. 97 (3): 709–16. doi:10.1111/j.1476-5381.1989.tb12007.x. PMC 1854580. PMID 2474351.

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