Abanoquil

Abanoquil (INN) is an α1-adrenergic receptor antagonist.[1]

Abanoquil
Clinical data
ATC code
  • none
Identifiers
IUPAC name
  • 2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-6,7-dimethoxyquinolin-4-amine
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC22H25N3O4
Molar mass395.459 g·mol−1
3D model (JSmol)
SMILES
  • COC1=C(C=C2CN(CCC2=C1)C3=NC4=CC(=C(C=C4C(=C3)N)OC)OC)OC
InChI
  • InChI=1S/C22H25N3O4/c1-26-18-7-13-5-6-25(12-14(13)8-19(18)27-2)22-10-16(23)15-9-20(28-3)21(29-4)11-17(15)24-22/h7-11H,5-6,12H2,1-4H3,(H2,23,24) Y
  • Key:ANZIISNSHPKVRV-UHFFFAOYSA-N Y
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See also

References
  1. Tham TC, Guy S, Shanks RG, Harron DW (April 1992). "Dose-dependent alpha 1-adrenoceptor antagonist activity of the anti-arrhythmic drug, abanoquil (UK-52,046), without reduction in blood pressure in man". British Journal of Clinical Pharmacology. 33 (4): 405–9. doi:10.1111/j.1365-2125.1992.tb04059.x. PMC 1381330. PMID 1349492.
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