2-OH-NPA

2-OH-NPA
Identifiers
	IUPAC name (R)-2,10,11-Trihydroxy-N-propylnoraporphine;
CAS Number	79640-85-0 ;
PubChem CID	6603798;
ChemSpider	8244599 ;
UNII	A88V5R3JGJ;
CompTox Dashboard (EPA)	DTXSID50274451 ;
Chemical and physical data
Formula	C19H21NO3
Molar mass	311.381 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES c4c3c2c(cc4O)-c1c(ccc(O)c1O)CC2N(CC3)CCC;
	InChI InChI=1S/C19H21NO3.BrH/c1-2-6-20-7-5-12-8-13(21)10-14-17(12)15(20)9-11-3-4-16(22)19(23)18(11)14;/h3-4,8,10,15,21-23H,2,5-7,9H2,1H3;1H/t15-;/m1./s1 ; Key:KIAIFHTWTMKEDI-XFULWGLBSA-N ;
	(verify)

2-OH-NPA is a drug used in scientific research which acts as a potent and selective agonist for the dopamine D₂ receptor.[1]

References

Gao YG, Baldessarini RJ, Kula NS, Neumeyer JL (June 1990). "Synthesis and dopamine receptor affinities of enantiomers of 2-substituted apomorphines and their N-n-propyl analogues". Journal of Medicinal Chemistry. 33 (6): 1800–1805. doi:10.1021/jm00168a040. PMID 1971309.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.