Prifinium bromide

Prifinium bromide is a pharmaceutical drug used primarily in the treatment of irritable bowel syndrome due to its action as an anticholinergic.[1]

Prifinium bromide
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
IUPAC name
  • 3-(Diphenylmethylene)-1,1-diethyl-2-methylpyrrolidinium bromide
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.022.774
Chemical and physical data
FormulaC22H28BrN
Molar mass386.377 g·mol−1
InChI
  • InChI=1S/C22H28N.BrH/c1-4-23(5-2)17-16-21(18(23)3)22(19-12-8-6-9-13-19)20-14-10-7-11-15-20;/h6-15,18H,4-5,16-17H2,1-3H3;1H/q+1;/p-1 Y
  • Key:UCGJZJXOPSNTGZ-UHFFFAOYSA-M Y
 NY (what is this?)  (verify)

Prifinium bromide's mechanism of action is believed to be due to its activity as an antispasmodic agent.[2]

Prifinium bromide is an antimuscarinic.[3]

References

  1. Piai, Guido (1975). "[Prifinium bromide in the treatment of the irritable colon syndrome]". Gastroenterology. 77 (3): 500–502. PMID 37142.
  2. Silber W (1979). "[Prifinium bromide-a new antispasmodic.]". South African Medical Journal. 56 (24): 1033–1034. PMID 45057.
  3. Magalini M, Monica F (June 1995). "[Use of prifinium bromide in endoscopic premedication. A double-blind controlled study vs hyoscine N-butylbromide]". Minerva Gastroenterologica e Dietologica. 41 (2): 197–202. PMID 7647144.
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