Tiemonium iodide

Tiemonium iodide is an antimuscarinic. It is poorly absorbed from the gut. The active moiety is tiemonium, a quaternary ammonium cation.[1]

Tiemonium iodide
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
IUPAC name
  • 4-[3-hydroxy-3-phenyl-3-(2-thienyl)propyl]-4-methylmorpholin-4-ium iodide
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard100.005.106
Chemical and physical data
FormulaC18H24INO2S
Molar mass445.36 g·mol−1
3D model (JSmol)
SMILES
  • C[N+]1(CCOCC1)CCC(C2=CC=CC=C2)(C3=CC=CS3)O.[I-]
InChI
  • InChI=1S/C18H24NO2S.HI/c1-19(11-13-21-14-12-19)10-9-18(20,17-8-5-15-22-17)16-6-3-2-4-7-16;/h2-8,15,20H,9-14H2,1H3;1H/q+1;/p-1
  • Key:IOFXEUZPIIUQAG-UHFFFAOYSA-M

References
  1. Scoular IT, Monks A, Burgess C, Turner P (1977). "Human studies on the bioavailability of a quaternary ammonium compounds, tiemonium iodide and tiemonium methosulphate". Current Medical Research and Opinion. 4 (10): 732–8. doi:10.1185/03007997609112009. PMID 1052164.
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