Diisopromine

Diisopromine or disoprominum, usually as the hydrochloride salt, is a synthetic spasmolytic[1] which neutralizes spastic conditions of the biliary tract and of the sphincter of Oddi. It was discovered at Janssen Pharmaceutica in 1955. It is sold in South Africa under the brand name Agofell syrup as a mixture with sorbitol,[2] and elsewhere as Megabyl.[3]

Diisopromine
Clinical data
ATC code
Identifiers
IUPAC name
  • N,N-Diisopropyl-3,3-diphenylpropan-1-amine
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.025.230
Chemical and physical data
FormulaC21H29N
Molar mass295.470 g·mol−1
3D model (JSmol)
SMILES
  • c1ccccc1C(c2ccccc2)CCN(C(C)C)C(C)C
InChI
  • InChI=1S/C21H29N/c1-17(2)22(18(3)4)16-15-21(19-11-7-5-8-12-19)20-13-9-6-10-14-20/h5-14,17-18,21H,15-16H2,1-4H3 Y
  • Key:YBJKOPHEJOMRMN-UHFFFAOYSA-N Y
  (verify)

See also

References
  1. Milne GW (2018). "6187: Diisopromine Hydrochloride". Drugs: Synonyms and Properties. London: Routledge. ISBN 978-1-351-78989-9.
  2. "AGOFELL® Syrup". South African electronic package inserts. Archived from the original on 20 September 2018. Retrieved 2 September 2015.
  3. "Guide des medicaments". Doctissimo. Retrieved 2 September 2015.



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