Cyclohexyl nitrite

Cyclohexyl nitrite is an organic compound, with formula C6H11NO2. It is the ester of cyclohexanol and nitrous acid, i.e. it is an alkyl nitrite. Like amyl nitrite and butyl nitrite, it acts as an antianginal due to vasodilation. The compound is colorless, volatile liquid.

Cyclohexyl nitrite
Clinical data
Other namesNitrous acid, cyclohexyl ester; N-Cyclohexyl nitrite; Cyclohexyl alcohol nitrite; C-hexyl nitrite; O-Nitrosocyclohexanol
ATC code
  • none
Identifiers
IUPAC name
  • cyclohexyl nitrite
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC6H11NO2
Molar mass129.159 g·mol−1
3D model (JSmol)
SMILES
  • O=NOC1CCCCC1
InChI
  • InChI=1S/C6H11NO2/c8-7-9-6-4-2-1-3-5-6/h6H,1-5H2 Y
  • Key:NRCNZCLHYWKEDX-UHFFFAOYSA-N Y
  (verify)

Safety

Inhaling the cyclohexyl nitrite vapor can lead to headache and dangerously low blood pressure.

Recreational use

Since early 2020 cyclohexyl nitrite has become popular as a recreational drug called poppers, mostly labeled as Canadian formula in various online stores that offer purchase of the drug. When used as an inhalant the effects are described as - stimulating ejaculation and orgasm, relaxation of sphincter muscles during anal sex, therefore making this compound appealing to the gay community, although users describe the experience as not even close compared to other alkyl nitrites.[1]

References

  1. Shapiro H, Buckle J (6 January 2016). "Nitrites". DrugWise.


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