Epidemiology of leprosy

In 2013, there were 550 cases, of which 277 were considered as new cases. Between 350 and 400 cases of leprosy are diagnosed every year.[12] In 1926 the law 11,359 ordered compulsory quarantine for the leper, that law was abolished by the law 22,964 in 1983, that ordered compulsory quarantine for the leper only if they refuse medical indications and involve some risk for the healthy population.

Five leper colonies were built:

• Pedro L. Baliña, Posadas, Misiones, opened on February 6, 1938.
• José J. Puente, San Francisco del Chañar, Córdoba, opened on March 18, 1939.
• Maximiliano Aberastury, Isla del Cerrito, Chaco, opened on March 30, 1939.
• Baldomero Sommer, General Rodríguez, Buenos Aires, opened on November 21, 1941.
• Enrique Fidanza, Colonia Ensayo, Entre Ríos opened on March 28, 1948.

Only the Baldomero Sommer continues serving as a leper colony.

Leprosy is a serious public health problem in Brazil, between 2001 and 2013 over 500,000 cases were reported and in 2015 alone over 25,000 cases were diagnosed.[13] There is evidence of hidden prevalence of leprosy.[14]

The People's Republic of China has many leprosy recovered patients who have been isolated from the rest of society.[15] In the 1950s the Chinese Communist government created "Recovered Villages" in rural remote mountaintops for the recovered patients. Although leprosy is now curable with the advent of the multi-drug treatment, the villagers remain because they have been stigmatized by the outside world.[15] Health NGOs such as Joy in Action have arisen in China to especially focus on improving the conditions of "Recovered Villages". The number of leprosy cases in China has been showing a steady decline over recent years, with a prevalence of 2697 registered cases in 2017 which is a 55.3% reduction compared to that in 2010.[16]

British India enacted the Leprosy Act of 1898 which institutionalized those affected and segregated them by sex to prevent reproduction. The Act was difficult to enforce but was repealed in 1983 only after MDT had become widely available. In 1983, the National Leprosy Elimination Programme, previously the National Leprosy Control Programme, changed its methods from surveillance to the treatment of people with leprosy. India reported a far larger decline in leprosy cases than any other country – from 473,658 new cases in 2002 to 161,457 in 2005.[17] According to WHO 16 million people worldwide were cured of leprosy since the past 20 years. India has estimated three million people with disability or health issues stemming from leprosy. India announced that leprosy had been “eliminated as a public health problem,” meaning that there would be fewer than one new case per 10,000 people (as defined by the WHO). Reported new cases exceed 125,000 per year (60% of the world total). 135,485 new leprosy cases were detected in India in 2017.[18][19]

Malaysia was announced to be eliminated of leprosy by WHO in 1994, which signifies a reduction in the prevalence rate of the disease to less than 1 case per 10,000 people. However, it was reported that there is a rise in incidence across the country over recent years, reaching 1.02 cases per 10,000 people in 2014.[20]

The Hospital-Colónia Rovisco Pais (the Rovisco Pais Hospital–Colony) was founded in Portugal in 1947 as a national center for the treatment of leprosy. It was renamed in 2007 as the Centro de Medicina de Reabilitação da Região Centro-Rovisco Pais. It still retains a leprosy service in which 25 ex patients live. Between 1988 and 2003 102 patients were treated in Portugal for leprosy.[21]

The Sanatorio de Fontilles (Fontilles Sanatorium) in Spain was founded in 1902 and admitted its first patient in 1909. In 2002, the Sanatorio had 68 in-patients in the Sanatorium, and more than 150 receiving out-patient treatment. A small number of cases continue to be reported.[22]

Two indigenous cases were reported from Greece in 2009.[23]

One case was reported in France in 2009[24]

Leprosy was almost eradicated in most of Europe by 1700 but sometime after 1850 leprosy was re introduced into East Prussia by Lithuanian rural workers immigrating from the Russian empire. The first leprosarium was founded in 1899 in Memel (now Klaipėda in Lithuania). Legislation was introduced in 1900 and 1904 requiring patients to be isolated and not allowed to work with others.

The last confirmed case of Leprosy being transmitted within the UK was in 1953.[25] Between 2003 & 2012, an average of 139 cases/year of leprosy were diagnosed (& notified) in the UK, none of which are believed to have been acquired within the UK.[25] The UK's national referral service for leprosy is run by Prof. Diana Lockwood, the UK's only Leprologist, at the Hospital for Tropical Diseases, London.[26]

The first documented case of leprosy (erga corpore morbi leprae) in Malta in a Gozitan woman (Garita Xejbais) was in 1492 but it is certain that it was present on the island before this time.[27] The next recorded case was in 1630 in a Dominican friar. A report in 1687 recorded five cases. A further three cases were reported in 1808. Between 1839 and 1858 an additional seven cases were recorded. In 1890 a population survey recorded a total of 69 cases. A later survey in 1957 identified 151 people infected with leprosy.

In June 1972 an eradication programme was started. The project was based on the work of Enno Freerksen, Director of the Borsal Institute in Hamburg. Dr Freerksen's earlier trial had used rifampacin, izoniazid, dapsone and prothionamide. The Malta project used rifampacin, dapsone and clofamazine. The project formally concluded in 1999 having treated about 300 patients.

The last leper colony in Europe is at Tichileşti, Romania. Until 1991 patients were not allowed to leave the colony. At this colony patients get food, a place to sleep, clothes and medical attention. Some live in long pavilions and others in houses with vegetable and flower gardens. There are two churches in the colony – Orthodox and Baptist – and a farm where the colony grows its own corn.

There were cases of leprosy in Atlantic Canada at the end of the nineteenth century, beginning in 1815.[28] The patients were first housed on Sheldrake Island in the Miramichi River and later transferred to Tracadie. Catholic nuns (the religieuses hospitalières de Saint-Joseph, RHSJ) came to take care of the sick. They opened the first French-language hospital in New Brunswick and many more followed. Many hospitals opened by the RHSJ nuns are still in use today. The last hospital to house lepers in Tracadie was demolished in 1991. Its lazaretto section had been closed since 1965. In a century of existence, it had housed not only Acadian victims of the disease, but people from all over Canada as well as sick immigrants from Iceland, Russia and China, among other nations.[29]

Cape Breton Island also suffered an outbreak, in the Lake Ainslie region. Nine people were affected, but it died out soon after 1882. Another outbreak of twenty cases occurred in the Lake O'Law region around 1852.[30]

In the United States, the first definite reference to the disease was in Florida in 1758. In 2004, there were 131 total cases of the disease in the United States. Of the 131 cases, two-thirds were male. Also out of the 131 cases, 25 (19%) were of individuals who were born in the country. Mexico (18.3%), Micronesia (11.5%), Brazil (9.2%), and the Philippines (7.6%) were the next leading countries where those with the disease were originally born. A total of 20 cases were found to be white, not of Hispanic origin. As of October, 2005, 3,604 patients on the United States registry were currently receiving care.[31] In 2018 there are about 5,000 people who no longer have leprosy but have long-term complications of disease and continue to receive care.[32] The disease is tracked by the Centers for Disease Control and Prevention (CDC), with a total of 166 new cases reported in the US in 2005. Most (100 or 60%) of these new cases were reported in California, Louisiana, Massachusetts, New York, and Texas.[33]