Etofamide

Etofamide (INN, also known as eticlordifene) is an antiprotozoal drug used in the treatment of amoebiasis.

Etofamide
Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration		Oral
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
IUPAC name
  • 2,2-dichloro-N-(2-ethoxyethyl)-N- [4-(4-nitrophenoxy)benzyl]acetamide
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.042.522
Chemical and physical data
FormulaC19H20Cl2N2O5
Molar mass427.28 g·mol−1
3D model (JSmol)
SMILES
  • CCOCCN(CC1=CC=C(C=C1)OC2=CC=C(C=C2)[N+](=O)[O-])C(=O)C(Cl)Cl
InChI
  • InChI=1S/C19H20Cl2N2O5/c1-2-27-12-11-22(19(24)18(20)21)13-14-3-7-16(8-4-14)28-17-9-5-15(6-10-17)23(25)26/h3-10,18H,2,11-13H2,1H3
  • Key:QTRALMGDQMIVFF-UHFFFAOYSA-N
  (verify)

Its effect against Giardia lamblia has been described as modest.[1]

References
  1. Cedillo-Rivera R, Muñoz O (September 1992). "In-vitro susceptibility of Giardia lamblia to albendazole, mebendazole and other chemotherapeutic agents". Journal of Medical Microbiology. 37 (3): 221–4. doi:10.1099/00222615-37-3-221. PMID 1518040.
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