Chlorquinaldol

Chlorquinaldol is an antimicrobial agent and antiseptic.[1] It is a chlorinated derivative of the popular chelating agent 8-hydroxyquinoline. It is applied topically as a cream and internally as a losenge.[2]

Chlorquinaldol
Names
Preferred IUPAC name
5,7-Dichloro-2-methylquinolin-8-ol
Other names
Anginazol; Lacoid, Nerisone
Identifiers
CAS Number
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.000.718
KEGG
PubChem CID
UNII
InChI
  • InChI=1S/C10H7Cl2NO/c1-5-2-3-6-7(11)4-8(12)10(14)9(6)13-5/h2-4,14H,1H3 Y
    Key: GPTXWRGISTZRIO-UHFFFAOYSA-N Y
  • InChI=1/C10H7Cl2NO/c1-5-2-3-6-7(11)4-8(12)10(14)9(6)13-5/h2-4,14H,1H3
    Key: GPTXWRGISTZRIO-UHFFFAOYAU
SMILES
  • Clc1c(O)c2nc(ccc2c(Cl)c1)C
Properties
Chemical formula
 C10H7Cl2NO
Molar mass 228.07 g/mol
Pharmacology
D08AH02 (WHO) G01AC03 (WHO), P01AA04 (WHO), R02AA11 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

It was marketed by Geigy as an intestinal antiseptic and amebicide with the trade name Siosteran.

References
  1. Mett H, Gyr K, Zak O, Vosbeck K (July 1984). "Duodeno-pancreatic secretions enhance bactericidal activity of antimicrobial drugs". Antimicrob. Agents Chemother. 26 (1): 35–8. doi:10.1128/aac.26.1.35. PMC 179912. PMID 6236746.
  2. Kutscher, Bernhard (2020). "Dermatologicals ( D ), 4. Antiseptics and Disinfectants ( D 08), Anti‐Acne Preparations ( D 10), and Other Dermatological Preparations ( D 11)". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. pp. 1–22. doi:10.1002/14356007.w08_w03.


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