Neticonazole

Neticonazole
Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	None;
Identifiers
	IUPAC name 1-{(E)-2-(Methylthio)-1-[2-(pentyloxy)phenyl]vinyl}-1H-imidazole;
CAS Number	130726-68-0 ;
PubChem CID	5282433;
ChemSpider	4445587 ;
UNII	KVL61ZF9UO;
ChEBI	CHEBI:135281;
CompTox Dashboard (EPA)	DTXSID4057633 ;
Chemical and physical data
Formula	C17H22N2OS
Molar mass	302.44 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCCCCOc1ccccc1/C(=C\SC)/n2ccnc2;
	InChI InChI=1S/C17H22N2OS/c1-3-4-7-12-20-17-9-6-5-8-15(17)16(13-21-2)19-11-10-18-14-19/h5-6,8-11,13-14H,3-4,7,12H2,1-2H3/b16-13+ ; Key:VWOIKFDZQQLJBJ-DTQAZKPQSA-N ;
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Neticonazole (INN) is an imidazole antifungal for the treatment of fungal skin infections.[1][2]

Neticonazole is only approved for use in Japan. It is sold as a topical ointment under the tradename Atolant.

References

Nimura K, Niwano Y, Ishiduka S, Fukumoto R (August 2001). "Comparison of in vitro antifungal activities of topical antimycotics launched in 1990s in Japan". Int. J. Antimicrob. Agents. 18 (2): 173–8. doi:10.1016/S0924-8579(01)00365-X. PMID 11516941.
Tsuboi R, Matsumoto T, Ogawa H (May 1996). "Hyperkeratotic chronic tinea pedis treated with neticonazole cream. Neticonazole Study Group". Int. J. Dermatol. 35 (5): 371–3. doi:10.1111/j.1365-4362.1996.tb03644.x. PMID 8734665. S2CID 34516725.

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