Picloxydine

Picloxydine (trade name Vitabact[1]) is a bisbiguanide antiseptic used in eye drops. It is structurally similar to chlorhexidine.

Picloxydine
Names
IUPAC name
1-N',4-N'-bis[N'-(4-chlorophenyl)carbamimidoyl]piperazine-1,4-dicarboximidamide
Identifiers
CAS Number
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.024.623
PubChem CID
UNII
InChI
  • InChI=1S/C20H24Cl2N10/c21-13-1-5-15(6-2-13)27-17(23)29-19(25)31-9-11-32(12-10-31)20(26)30-18(24)28-16-7-3-14(22)4-8-16/h1-8H,9-12H2,(H4,23,25,27,29)(H4,24,26,28,30) N
    Key: YNCLPFSAZFGQCD-UHFFFAOYSA-N N
  • InChI=1/C20H24Cl2N10/c21-13-1-5-15(6-2-13)27-17(23)29-19(25)31-9-11-32(12-10-31)20(26)30-18(24)28-16-7-3-14(22)4-8-16/h1-8H,9-12H2,(H4,23,25,27,29)(H4,24,26,28,30)
    Key: YNCLPFSAZFGQCD-UHFFFAOYAM
SMILES
  • C1CN(CCN1C(=NC(=NC2=CC=C(C=C2)Cl)N)N)C(=NC(=NC3=CC=C(C=C3)Cl)N)N
Properties
Chemical formula
C20H24Cl2N10
Molar mass 475.37756
Pharmacology
S01AX16 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

References

  1. Obikili AG, Oji EO, Shonekan RO, Otti P (1988). "A double-blind comparison of picloxydine dihydrochloride (Vitabact eye drops) and sulfacetamide eye drops in the topical therapy of trachoma". Revue Internationale du Trachome et de Pathologie Oculaire Tropicale et Subtropicale et de Santé Publique. 65 (3–4): 119–32. PMID 3274675.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.