Azidamfenicol

Azidamfenicol is an amphenicol antibiotic,[1] which has similar profile to chloramphenicol. It is used only topically, as eye drops and ointment for treatment of susceptible bacterial infections.[2]

Azidamfenicol
Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration		Topical (ocular)
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
IUPAC name
  • 2-azido-N-((1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl)acetamide
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.034.125
Chemical and physical data
FormulaC11H13N5O5
Molar mass295.255 g·mol−1
3D model (JSmol)
Melting point99 to 107 °C (210 to 225 °F)
SMILES
  • [N-]=[N+]=N\CC(=O)N[C@@H]([C@H](O)c1ccc([N+]([O-])=O)cc1)CO
InChI
  • InChI=1S/C11H13N5O5/c12-15-13-5-10(18)14-9(6-17)11(19)7-1-3-8(4-2-7)16(20)21/h1-4,9,11,17,19H,5-6H2,(H,14,18)/t9-,11-/m1/s1 Y
  • Key:SGRUZFCHLOFYHZ-MWLCHTKSSA-N Y
 NY (what is this?)  (verify)

References
  1. de Groot AC (2021). "Chaper 3.26: Azidamfenicol". Topical Drugs. Monographs in Contact Allergy. Vol. 3 (First ed.). Boca Raton, FL: CRC Press. p. 79. ISBN 978-1-00-036786-7.
  2. Sweetman SC (2007). Martindale: The Complete Drug Reference (35th ed.). London: Pharmaceutical Press. ISBN 978-0-85369-687-2.
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