Reactive perforating collagenosis

Reactive perforating collagenosis is a rare, familial, nonpuritic skin disorder characterized by papules that grow in a diameter of 4 to 6mm and develop a central area of umbilication to which keratinous material is lodged.[1][2] The cause of reactive perforating collagenosis is unknown.

Reactive perforating collagenosis
SpecialtyDermatology 

Clinical Features

Inherited form

Keratotic papules measuring 1 to 6 mm develop on the extensor surface of the hands, the elbows, and the knees following superficial trauma. These lesions are painless. They appear as pin-sized lesions that grow to a papule of about 6mm in the following 3–5 weeks. They undergo spontaneous resolution in about 6–8 weeks leaving residual scarring. Lesions may recur throughout life. Cold weather is one of the factors known to trigger recurrences.[3]

Acquired form

In this form, keratotic papules develop on the trunk and extremities. These are commonly associated with pruritus. Lesions may or may not be related to superficial trauma.[3]

See also

References
  1. James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. Page 510. ISBN 0-7216-2921-0.
  2. Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 978-1-4160-2999-1.
  3. Ngan, Vanessa; Writer, Staff (2005). "Reactive perforating collagenosis". DermNet NZ. Retrieved 30 June 2021.{{cite web}}: CS1 maint: url-status (link)


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